Improved Plug-N-Play Adaptive Opics Device

Description

Enhanced plug & play adaptive optics device, called MicAO, is now compatible with a larger range of objective lenses and larger field of view cameras, such as sCMOS.

 

By correcting the system and sample-induced aberrations, MicAO allows users to significantly improve the image contrast in spinning disk microscopy and to increase the 3D localization precision in single molecule detection methods using aberration-free astigmatism (3D PALM/STORM). This ability to correct aberrations allows the user to image cellular structures deeper in biological samples, up to a depth of 50µm.

Specs

Highlights:

  • compatible with larger range of objective lenses
  • accommodates larger field-of-view cameras, such as sCMOS
  • user can improve image contrast in spinning disk microscopy
  • corrects aberrations
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